Our Research Approach
Our laboratory investigates the neural mechanisms underlying autism spectrum disorder using advanced models. Our research focuses on brain regions involved in social behavior, including the limbic system, basal ganglia, midbrain, and cerebellum. We use molecular, anatomical, and behavioral techniques to explore how changes at the cellular level contribute to ASD-related phenotypes.
Our Methods
Behavioral
We use an array of behavioral assays to assess social interaction, fight-or-flight, and developmental milestones in advanced models of autism. These include the three-chamber social preference test, novel versus non-novel object enrichment, and age-specific developmental tests.
Immunohistology
Our lab combines immunohistology with viral tracing techniques to investigate the brain circuits underlying autonomic function. We use trans-synaptic transport of neurotropic tracers to trace multi-synaptic neural networks. This approach allows us to generate high-resolution, brain-wide maps of autonomic control.
Anatomy
We apply a range of anatomical techniques to define the structural organization of brain regions involved in autonomic control. These include high-resolution tissue sectioning, stereotactic brain mapping, and neuroanatomical tracing using viral and chemical markers.
Join the team!
We’re always eager to welcome new ideas and dedicated individuals to our lab. If you’re passionate about autism research and neuroscience, come grow with us. Reach out to learn how to get involved!
